About the study

Study overview

The RELIANCE Clinical Research Program is currently testing an investigational medication for people living with depression. If you have been diagnosed with depression, are currently experiencing symptoms, sometimes referred to as a depressive episode, and are between the ages of 18-65 years, you may be eligible to participate.

This program includes studies for people who are not currently taking an antidepressant or who are currently taking antidepressants but find that they are not fully managing your symptoms. If you are taking an antidepressant and are eligible for one of these studies, you may be able to continue with your current antidepressant in addition to using the investigational medication.

People who enroll in a study will be randomly assigned (like the flip of a coin) to a study treatment group to take either the investigational medication or a placebo. There is an equal chance (50/50) of being assigned to either group. Neither you nor the study doctor will know whether you are assigned to the treatment or placebo group. After completing one of these studies, as a participant you will have the opportunity to join a longer open label study. In the open label study, all participants will receive the investigational medication for up to 1 year. The purpose of this open label study is to continue evaluating the investigational medication over a longer treatment period.

image of participant asking about study duration

Study duration

How long will the study last?

The studies in the RELIANCE Clinical Research Program have two groups (investigational medication and placebo) and may last up to ten weeks. This time includes a screening period, a treatment period, and a follow-up period. You can stop your participation in the study at any time.

In the open label study, all participants will receive the investigational medication for up to 1 year.

See if you pre-qualify

How long will the study last?

  • To receive frequent health check-ups
  • To help others by expanding what we know about depression and its treatment
  • You may gain additional resources for managing your depression

Refer a friend

Do you know someone between the ages of 18-65 who is living with depression? They may be eligible to participate in one of the RELIANCE research studies. Consider sharing information with them about how they can learn more.